Port St Lucie’s Top 10 Spas & Spa Therapists

The Profile

Port St. Lucie Medical Wellness operates as a combined medical and aesthetic clinic offering an unusually broad menu that includes injectables such as BOTOX, Dysport and Xeomin, dermal fillers including Restylane and Sculptra, IPL and laser services, hydrodermabrasion and advanced skin therapies alongside IV drips and peptide treatments.

The team mixes advanced clinical credentials with aesthetic practice: clinicians listed include Brooke Harper DNP APRN FNP-BC, Harsha Setty MD MBA and Alyssa Dagostino MSN APRN. The clinic also promotes regenerative options such as PRP injections and exosome therapies plus hormone replacement programs for men and women, showing an emphasis on medically supervised wellness.

Beyond procedure variety the practice supports ongoing care through VIP membership options, a RepeatMD booking app presence, regular specials and financing. The clinic publishes a gallery of before-and-after cases and stresses individualized treatment planning that pairs aesthetic procedures with weight loss and hormone services for sustained results.

Why It Made the List and Why It’s Our Top Pick

Port St. Lucie Medical Wellness ranks highest because it pairs a medical team and a wide procedural toolkit in one location, allowing clients to combine injectables, laser resurfacing, IV therapy and semaglutide-supported weight management under the same roof for coordinated aesthetic and wellness plans.

Good to Know

Book a consultation to confirm suitability and sequencing of medical and cosmetic treatments; the clinic is on, open Monday through Friday 9: 00 AM to 5: 00 PM and offers specials, VIP membership perks and financing via the RepeatMD app.

The Profile

The Spa at St. Lucie West is a boutique day spa tucked into the office condominiums behind the old St. Lucie West Publix, positioning itself as a petite retreat. Services include facials, manicures, pedicures, hair removal, anti-aging skin treatments, hairstyling and curated spa packages designed for time-limited appointments.

Appointments are offered by design Tuesday through Saturday and the business emphasizes personalized attention from licensed, educated practitioners. The spa explicitly requests that clients reschedule if they have illness symptoms, and it highlights a mission to deliver professional, sanitized manicures and pedicures alongside tailored skin and hair services.

Why It Made the List

This spa’s notable advantage is its close, appointment-driven attention: the Petite Retreat model and licensed staff prioritize tailored treatments that match a client’s schedule and needs, producing carefully judged, professional finishes in every manicure, facial and package treatment.

Good to Know

The business operates by appointment only and asks guests to reschedule if they have illness symptoms; the spa is located behind the old Publix in St. Lucie West and can be reached at the local phone number listed for bookings.

The Profile

Sejour Body Bar Wellness Med Spa in Port St. Lucie advertises an advanced treatment menu including Morpheus8 microneedling radiofrequency, CO2 laser procedures and injectable treatments. The clinic pairs facial balancing injectables with signature facials and offers body contouring technologies alongside aesthetic lasers to address skin laxity and textural concerns.

The practice also runs medical-style weight management that uses semaglutide, plus a VIP program and payment-plan options. Their published hours are Tuesday through Saturday, and the clinic lists a local contact number and an email for booking, indicating a small medical-aesthetic team focused on combined wellness and cosmetic outcomes.

Why It Made the List

Sejour’s defining strength is the combination of cutting-edge technologies such as Morpheus8 and CO2 laser with an on-site semaglutide weight-management program, allowing clients who want both contouring and metabolic support to follow a coordinated, medically informed plan.

Good to Know

First-visit incentives and a VIP program are part of Sejour’s offer; the clinic publishes Tuesday–Saturday hours and recommends reserving a ‘Get To Know You’ consultation to map treatments, financing options and any required pre-treatment planning.

The Profile

Natural Spa & Massage offers a broad spa service list that centers on full-body massage, facial options and body exfoliation, with waxing and threading included for comprehensive grooming. The venue highlights restorative care and a range of spa specials intended to leave clients feeling refreshed and rejuvenated after each session.

Alongside standard spa services the business promotes DDS bioelectric therapy and sauna sessions as part of its treatment mix, and it advertises over twenty years of combined practitioner experience plus competitive pricing and attractive discounts, positioning itself as a practical choice for regular spa maintenance.

Why It Made the List

Natural Spa & Massage stands out for integrating traditional spa treatments with therapeutic modalities such as DDS bioelectric therapy and dedicated sauna options, creating a blend of relaxation and modality-driven therapeutic care for ongoing wellbeing.

Good to Know

The salon runs specials and offers gift certificates; callers are encouraged to request an appointment and confirm available treatment times, noting the practice emphasizes competitive pricing and package options for repeat visits.

The Profile

The Sanctuary Spa is a long-established luxury spa in St. Lucie West celebrating two decades in business and a recent expansion to roughly 2, 500 square feet of treatment space. The facility emphasises sensory comforts such as aromatherapy and tranquil soundscapes and offers a polished environment for extended relaxation sessions.

Its treatment menu lists more than fifty specialty options including signature services, massage and body work, facial therapies and bespoke packages. The location sits at the corner of Country Club Drive and St. Lucie West Boulevard and the spa publishes both standard contact lines and an after-hours spa concierge text option for urgent booking queries.

Why It Made the List

The Sanctuary’s combination of extensive floor space, a long-established team and an unusually wide menu of over fifty specialty treatments makes it a top pick for clients seeking a one-stop, luxury-focused spa that can accommodate multi-hour rituals and gift purchases.

Good to Know

You can purchase gifts online and use a JotForm booking link for appointments; phone bookings are accepted and an after-hours ‘spa concierge’ text line is provided for urgent scheduling needs beyond normal business hours.

The Profile

Ashe Wellness and Spa suite 114 operates from a suite-based setting that foregrounds private, one-on-one appointments and restorative spa treatments in a compact environment. The practice highlights a considered appointment style aimed at producing a polished, natural finish and a calm client experience within a small professional space.

The business emphasizes steady, reliability-focused care rather than high-volume turnover: appointments are handled with consistent attention and an emphasis on suitability, so treatments are adapted to a client’s needs rather than delivered from an exhaustive, generic menu.

Why It Made the List

Ashe’s distinguishing feature is its suite-model delivery of wellness and spa services, which supports focused, individualized sessions that prioritize outcome consistency and careful treatment selection over rapid throughput or broad, unfocused menus.

Good to Know

Located in Suite 114, this small-suite practice typically sees clients by appointment; expect a private setting with a small team and plan to contact the studio ahead to confirm scheduling and treatment availability.

The Profile

SkinRise Wellness & MedSpa promotes a technology-forward menu that includes Morpheus8 radiofrequency microneedling, IPL Lumecca Peak treatments, LHR Fusion for light/dark hair removal, CO2 laser resurfacing and PicoLaser options, placing an emphasis on advanced skin-rejuvenation tools alongside facials and body treatments.

The clinic supports ongoing client relationships through memberships and a loyalty program, provides medspa injectables and body-contouring treatments, and maintains an online booking and consultation workflow that encourages clients to reserve an initial consultation before committing to multi-session protocols.

Why It Made the List

SkinRise’s strength is its concentration on advanced laser and body-sculpting technologies combined with membership and loyalty structures, making it a practical choice for clients who plan multi-session regimens and want access to a consistent treatment pathway.

Good to Know

SkinRise offers memberships and a loyalty program and requests that clients book consultations through its online booking system; follow @skinrise.medspa on Instagram for treatment updates and before-and-after examples.

The Profile

Advanced Med SPA - Port St. Lucie is presented as a local medspa located on Southwest Port Saint Lucie Boulevard and described in available listings as a clinic-oriented facility offering restorative and aesthetic services in a peaceful setting. The practice emphasizes refinement and dependable finishes delivered in a calm environment.

The venue highlights attention to detail, measured treatment planning and a quiet, clinic-like atmosphere that supports predictable results. The presentation across listings stresses careful service delivery rather than high-volume cosmetic packages, positioning it as a neighborhood medspa focused on consistent outcomes.

Why It Made the List

Advanced Med SPA merits consideration for clients who prefer a measured, clinic-like spa visit: the business projects a refined, dependable approach with emphasis on detail and a tranquil atmosphere suitable for medically informed aesthetic procedures.

Good to Know

The medspa is listed as operating on Southwest Port Saint Lucie Boulevard and typically schedules by appointment; prospective guests should confirm current booking availability directly with the clinic before visiting.

The Profile

Ping’s Spa describes a mission of harmonizing Eastern and Western techniques and offers a focused menu of massage therapies intended to combine physical healing with relaxation. The studio lists therapeutic, Swedish and deep-tissue approaches alongside sports massage and lymphatic drainage to address a variety of muscular and recovery needs.

Additional specialized services include pregnancy massage, hot-stone therapy, cupping and a unique back-walking modality; the studio provides license details and a local phone number and operates from a suite on SW St. Lucie West Boulevard with clearly posted operating hours for select weekdays.

Why It Made the List

Ping’s Spa stands out because of its broad and specific massage repertoire plus a holistic healing philosophy, offering modalities that cater to athletic recovery, pregnancy care and traditional relaxation within the same studio framework.

Good to Know

Ping’s Spa posts weekday hours of operation (for example, Monday, Tuesday, Thursday and Friday mornings to early afternoons) and is located at Suite 110, so confirm exact appointment times by calling the local phone number before you travel.

The Profile

Bella Body and Spa presents itself as a neighborhood destination for restorative spa treatments delivered in a calm, small-staff environment. The business emphasizes a professional yet personal approach to skincare and body therapies, aiming for results that feel natural and wearable after clients leave the treatment room.

The spa underscores consistent appointment handling and attention to suitability so that each service is tailored rather than generic. This local focus gives clients a predictable, professionally handled experience intended to leave skin and body treatments feeling polished and reliable over time.

Why It Made the List

Bella Body and Spa’s distinguishing quality is its neighborhood-scale focus on producing carefully judged, lasting results through attentive, individualized treatments delivered in a relaxed clinic atmosphere rather than a high-volume salon setting.

Good to Know

Appointments are recommended because the spa emphasizes tailored sessions; prospective clients should check availability in advance and expect a calm, small-team setting focused on treatment suitability and longer-term results.